The Club for Growth is targeting U.S. Sen. Elizabeth Dole.

The free-market group is spending $250,000 on radio and television spots against Dole and five other senators over a bill that aims to reduce greenhouse gas emissions.

"Congress is at it again. This time, they're pushing massive new taxes and regulations in the name of global warming," says the narrator of the ad over dramatic music.

The ad then cites a study commission by the National Association of Manufacturers which found that the state could lose 146,000 jobs per year and see a 135 percent increase in electricity prices

Dole, who is running for re-election this year, is a co-sponsor of the measure sponsored by Sen. Joe Lieberman, a Connecticut independent, and Sen. John Warner, a Virginia Republican.

"Call Sen. Elizabeth Dole today," the narrator says. "Tell her to vote no on the Lieberman-Warner climate bill. North Carolinians just can't afford another huge costly government program."

Update: Dole was one of the original co sponsors of the legislation that would rely on a "cap and trade" program to give American companies a financial incentive to reduce their greenhouse gas emissions, Rob Christensen reports.

Dole has also been subject to an automated telephone calling campaign by a group financed by coal companies according to Elizabeth Ouzts of Environment North Carolina.

She said environmentalists thnink the Lieberman-Warner bill does not go far enough and provides too many financial incentives to companies.

A transcript after the jump.

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A blogger for the anti-tax Club for Growth included U.S. Sen. Richard Burr on a list of potential vice presidential candidates for John McCain.

As far as the Burr Veep Watch goes, that doesn't mean much, since the list includes 32 other potential vice presidents, "some common and some uncommon."

Still, Burr scored well, considering the list was centered around the pick's age. He is 52.